Cardiovascular Complications of Cutis Laxa Syndrome

Cardiovascular complications of cutis laxa syndrome: successful diagnosis and surgical management.

Cutis laxa syndrome is a rare inherited connective tissue disorder characterized by inelastic loose hanging skin, which gives the appearance of premature aging. Histology shows degenerative changes in the elastic fibers of the connective tissue throughout the body. Severe aortic dilatation may occur because of medial elastic fiber degeneration. We report the case of a 27-year-old man with a con...

Sotos syndrome and cutis laxa.

Characteristics suggestive of connective tissue dysfunction have been described in Sotos syndrome and include joint hyperextensibility, pes planus, and a high arched palate. A variety of cutis laxa syndromes have also been described, some of them exhibiting mental retardation, but no reports have drawn an association with overgrowth or abnormal facies characteristic of Sotos syndrome. We report...

Cutis laxa: a feature of Costello syndrome.

Cutis laxa and the Costello syndrome.

Cutis Laxa syndrome: a case report

Cutis laxa (CL) is a heterogeneous group of inherited and acquired connective tissue disorders characterized by a loose skin and variable systemic involvement (inguinal hernia, cardiopulmonary disease, and emphysema). Autosomal dominant, autosomal recessive and x-linked recessive patterns have been described in the inherited forms. Acquired forms of this disease have been associated with a prev...